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Prami
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Prami - 02-24-2013, 12:33 PM

I'm new to prami and would be interested in researching it so I started reading. Everything I've found is regarding its usage with letro and/or while on cycle. I'm curious about its usage alone and off cycle for, what I've read, the reversal of small gyno symptoms.
   
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02-24-2013, 01:11 PM

My understanding is that it is pretty much like Letro and like you said for minor gyno issues. I just stick with Letro or Nolva.
   
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02-24-2013, 01:13 PM

Here is what I found on a quick search:

Prolactin suppression using Pramipexole

For Prevention: when you are taking something that can cause prolactin issues or when you just want to lower prolactin, for the benefits of lowering prolactin.

0.125 (1/8) to 0.5mg (1/2) per day should generally be sufficient for most users. With prevention slow escalation should not be an issue

For Treatment: When you have ongoing prolactin issues, Gynecomastia flare, or are attempting to regress gynecomastia tissues (ductal, lobular and central gland mass).

0.375 up (3/8) to 1mg should generally be sufficient for most users. Most people will not need over 0.5mg. If you do, then SLOWLY escalate the dose. You still should start at 0.25mg and slowly work up. see bottom for exceptions

doses should be taken in the evening, 2-4 hours prior to bed. For the very low doses, an hour is probably fine. if it keeps you up, take it earlier. If it makes you sleepy "too soon" then take closer to bed. a good number of people will notice niether. taking with last meal of the day may be ideal for a lot of people.

Now for you people that want high end dosing benefits, which are not prolactin suppression. This is a lot more complex, and generally requires a VERY slow progression in dosing to acheive. Clinicals increased the dose by 0.125 every 3-5 days. there will typicallly be side effects for people at various point along the progression. IT IS EXTREMELY IMPORTANT THAT YOU BE AWARE OF THESE BEFORE YOU LAUNCH INTO HIGH END DOSING.

IMPORTANT NOTE

For those that do not have dopaminergic sides, other than "waking up from sleep"-- which is caused by the drop in pramipexole in the plasma and the subsequent surge of dopamine release from the tissues in which they were suppressed, JUMPING the dose up more quickly will generally alleviate this. this is for those for whom interupted sleep is the primary and pretty much only side effect. this applies to treatment and high end dosing (at least until sleep interution abates).
   
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02-24-2013, 07:51 PM

Careful with prami. It's pretty strong and can make you sick as hell. Anything over .2mg and I would throw up. Use it for prolactin. Issues. If you have gyno flare up use letro (some people swear by nolva). Letro is strong and tough on Lipids
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02-24-2013, 08:10 PM

Quote:
Originally Posted by thebull2012 View Post
I'm new to prami and would be interested in researching it so I started reading. Everything I've found is regarding its usage with letro and/or while on cycle. I'm curious about its usage alone and off cycle for, what I've read, the reversal of small gyno symptoms.
What type of gyno do you have? What aas are you taking? Generally prami is not needed unless taking tren or high doses of deca. It is incredible with tren due to dopamines effects on anxiety too. If used I would start at 0.1mg per day a few hours pre bed for 1 week. Then possibily move up to 0.2mg if needed. It is very strong so you need to be careful with the dosing. The article proFIT posted is excellent. Just adding the only prami I have used is ergo's and that was great for me when I used 50mg tren a daily. I am actually gonna start it again tonight as I have just begun my big blast with 300mg test and 1.2g deca... 0.1mg daily and no more

Just a few tips an AI such as aromasin/arimidex are good on cycle to prevent estrogenic sides. A good method for estrogenic gyno is to start with nolva and move up to letro if the first is not strong enough. However in my experience nolva is great for gyno and all I have ever needed. 20mg per day should be more than enough to help with gyno. More aggressive dosing may be required if the gyno is bad. Nolva is my fav and doesn't give me any sides and has always been great for me.

Letro can cause many issues at effective doses. 2.5mg per day is best if the gyno is bad. That could be combined with 10-20mg nolva if the gyno is is really bad and has been left awhile. Letro will dry you out fast so your joints will ache so avoid heavy lifting when using it. That dose should also kill your sex drive over time depending upon what your using. One benefit if your bf is fairly low to begin with letro will get you looking ripped


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Last edited by Elvia1023; 02-24-2013 at 08:12 PM.
   
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Prami - 02-24-2013, 08:57 PM

I feel the need for Prami or any other prolactin related ancillary can be averted by the use of Masterone.

Masterone is like the all in one drug... I am super gyno prone and was having a hard time getting rid of some gyno. Found a great article about using Masterone and low dose Letro- boom it was gone. This use of Masterone opened up the idea of other uses or how it could be used aside from its more common uses. I have been writing so much about Mast that I am tired of it honestly but if you want me to get into it more I will.

I'm simply saying that for 95% of the times you'd think of needing Prami- Masterone will do the job better with less sides and for more benefits.
   
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