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orals

thc

New member
Feb 2, 2012
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How true is that if you take your orals with citrus juice it increases the power of the pills? Or is just another myth?
 

ASHOP

AnaSCI VET
Aug 28, 2005
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ashop.in
How true is that if you take your orals with citrus juice it increases the power of the pills? Or is just another myth?

Its grapefruit juice and it does that to alot of other prescription medications. Its not just a myth. Ive not heard that it makes oral AAS stronger or more effective though.
 

kevin

Registered User
May 6, 2011
62
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Far as I know grapefruit juice it help increase absorption rate when taken in conjunction with orally applicable drugs
 

thc

New member
Feb 2, 2012
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does this also work for injectables like eq and test ?
 
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alfred

Registered User
Apr 30, 2011
165
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In fact medical studies have shown GF juice to be so effective at increasing absorption of oral meds that they have had to warn users of prescription meds with possible overdose potential not to use GF juice at all.
 

danny

Registered User
May 11, 2011
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In fact medical studies have shown GF juice to be so effective at increasing absorption of oral meds that they have had to warn users of prescription meds with possible overdose potential not to use GF juice at all.

Definitely agree! THis is very true..
 

thc

New member
Feb 2, 2012
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In fact medical studies have shown GF juice to be so effective at increasing absorption of oral meds that they have had to warn users of prescription meds with possible overdose potential not to use GF juice at all.

interesting stuff bro.
 

Rioba0.2

New member
Jan 6, 2012
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In fact medical studies have shown GF juice to be so effective at increasing absorption of oral meds that they have had to warn users of prescription meds with possible overdose potential not to use GF juice at all.

nice, that is something I didn't know.
 

willI'm

New member
Jul 5, 2011
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I don’t understand very well, you're saying grapefruit juice doesn't help with liquid orals?
 

snatch

Registered User
May 8, 2012
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WARNING: The reason doing this is contraindicated is because dosages for potentially harmful drugs (Viagra) are based on average absorption with ACTIVE CYP3A4 in normal populations. Inhibiting your CYP3A4 can easily cause overdose of certain medications with potentially dangerous consequences.

If you drink grapefruit juice before your dose, YOU ARE TAKING MORE OF THE DRUG THAN YOU THINK.

READ THE WARNING

Grapefruit juice and the flesh and rind of the grapefruit contain Bergamottin, a moderate inhibitor of the enzyme CYP3A4 in the small intestine. CYP3A4 is present in large quantities in the liver and is responsible for the metabolism of MANY compounds. In the small intestine, it eliminates these compounds before they can be absorbed. Inhibition of CYP3A4 in the intestine results in increased rate and total absorption of its substrates, which include these drugs of interest to you guys:

  • Tamoxifen (Nolvadex)
  • Anastrozol (Arimidex)
  • Toremifene
  • Oral Testosterone (Dianabol, Anadrol, etc)

Also potentially of interest:
  • Sildenafil (Viagra)
  • Diazepam/Alprazolam (Valium/Xanax)
  • Codeine
  • Most SSRIs and beta blockers
  • Most tricyclic antidepressants
  • Some antibiotics
  • Caffeine

So basically, drinking 250ml (the smallest quantity I've seen in the literature) of pure grapefruit juice (not juice cocktail) 5-15 minutes before taking one of these drugs can increase both the amount absorbed and the rate of absorption.

If you want to experiment with this and you're a regular coffee drinker, drink 250-500ml of grapefruit juice before your normal amount of coffee in the morning. You'll easily notice that the caffeine affects you much more than it should.

Important: Don't think this means you can be cheap and take less dbol for the same effect (at least one person always asks this question). Nobody can tell you exactly how much of an effect you're going to get, so there's no way to confidently say what an equivalent dose would be. All this means is that, if you're already taking a dose you're very comfortable with, you can get a little more effect out of it by taking it with grapefruit juice.

If you're taking a dose that's already as much as you should take, then adding grapefruit juice may give you undesirable side effects or make the side effects worse.
 
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