- Apr 2, 2009
- 1,675
- 0
- 0
The stability of a liquid solution of LR3IGF-I was monitored for a
period of two years at storage conditions of -20 C, +4 C, +22 C,
and +37 C. The final concentration of LR3IGF-I was in acetic acid.
At various time points, samples were taken and compared to a
lyophilized control (stored at 4 C). Listed below are the stability
results for each respective storage condition.
Storage Condition: -20 C (-4 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years
Storage Condition: +4 C (39.2 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years
Storage Condition: +22 C (71.6 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years
Storage Condition: +37 C (98.6 F)
Biological Potency No Change up to 1 year
Immunological Activity No Change up to 1 year
Mobility of Protein No Change up to 1 year
Elution Profile by reversed phased HPLC No Change up to 1 year
Bacteriostatic can still be used, but IGF calls for Acetic Acid since it`s the PH levels in the acid that maintain the integrity and quality of the IGF...BW reconstitution will last for about 1 to 2 weeks on average...
period of two years at storage conditions of -20 C, +4 C, +22 C,
and +37 C. The final concentration of LR3IGF-I was in acetic acid.
At various time points, samples were taken and compared to a
lyophilized control (stored at 4 C). Listed below are the stability
results for each respective storage condition.
Storage Condition: -20 C (-4 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years
Storage Condition: +4 C (39.2 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years
Storage Condition: +22 C (71.6 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years
Storage Condition: +37 C (98.6 F)
Biological Potency No Change up to 1 year
Immunological Activity No Change up to 1 year
Mobility of Protein No Change up to 1 year
Elution Profile by reversed phased HPLC No Change up to 1 year
Bacteriostatic can still be used, but IGF calls for Acetic Acid since it`s the PH levels in the acid that maintain the integrity and quality of the IGF...BW reconstitution will last for about 1 to 2 weeks on average...