As long as I taper off the HcG as the last of the drugs exit my system, I'm then ready to begin the arduous task of waiting for my body to come back online. It takes a while. While I wait though, I can make myself a LOT more comfortable (and my girl). You wouldn't think an AI and prolactin inhibitor with some amino acids could make such a difference. No protocol necessary. I would take small amounts of cabergoline and my aminos no matter what I did.
With Aromasin (exemestane), cabergoline, along with L-dopa and L-tyrosine for additional GnRH support until my body decides to increase GnRH, I can:
provide GnRH and LH support
reduce SHBG and increase free T
lower estrogen
lower prolactin
maintain healthy lipid profile
(see info and links below)
Suppression of estrogen, via estrogen receptor or aromatase blockade, is being investigated in the treatment of different conditions. Exemestane (Aromasin) is a potent and selective irreversible aromatase inhibitor. To characterize its suppression of estrogen and its pharmacokinetic (PK) properties in males, healthy eugonadal subjects were recruited. In a cross-over study, 12 were randomly assigned to 25 and 50 mg exemestane daily, orally, for 10 d with a 14-d washout period. Blood was withdrawn before and 24 h after the last dose of each treatment period. A PK study was performed (n = 10) using a 25-mg dose.
The 25- and 50-mg doses of daily exemestane had comparable effects in suppressing circulating estrogen concentrations, with 38 ± 24% (mean ± SD; P = 0.002 vs. baseline) and 32 ± 29% (P = 0.008)
decreases in estradiol concentrations, 71 ± 12% (P < 0.0001) and 74 ± 12% (P < 0.0001)
decreases in estrone concentrations, and 45 ± 27% (P = 0.004) and 51 ± 20% (P = 0.02)
There was an
increase in circulating testosterone concentrations after both 25 mg (60 ± 58%; P = 0.001) and 50 mg (56 ± 48%; P = 0.003) exemestane.
Androstenedione concentrations were increased as well after 25 mg (32 ± 36%; P = 0.004) and 50 mg (47 ± 59%; P = 0.052) exemestane, respectively (Fig. 1Go and Table 2Go).
SHBG concentrations were decreased by 21 ± 7% (P = 0.0003) and 19 ± 39% (P = 0.18) at 25 and 50 mg exemestane, respectively.
Free testosterone concentrations were increased by 117 ± 74% (P = 0.0001) and 154 ± 95% (P < 0.0001) at both doses, due to the decrease in SHBG and the increase in total testosterone.
Pharmacokinetics and dose finding of... [J Clin Endocrinol Metab. 2003] - PubMed - NCBI
Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males