©ALL CONTENT OF THIS WEBSITE IS COPYRIGHTED AND CANNOT BE REPRODUCED WITHOUT THE ADMINISTRATORS CONSENT 2003-2020



Ketoconazole Help Prevent Hairloss?

MaSTa LifTa

Registered User
Apr 29, 2005
794
0
0
I was wondering if anyone could explain to me how Nizoral which contains ketoconazole, an antifungal, could prevent hairloss? Anyone know the mechanism???
 

MaSTa LifTa

Registered User
Apr 29, 2005
794
0
0
Hey, I don't think anyone else is interested in this, but here it is anyway:

Nizoral(ketoconazole) Mildly inhibits the binding of DHT to the hair follicle androgen receptor. Additionally it likely suppresses the localized autoimmune responses through its effects on specific cytokines that are related to dandruff and perifollicular inflammation (present in 98% of balding men).

There have been 2 studies published in the medical literature confirming that 2% Nizoral shampoo grows hair in balding men with continued usage. It appears to cure scalp inflammation and reduces sebum levels confirming its antiandrogenic effect. Numerous anecdotal reports and a recent study would seem to indicate that the 1% over the counter version is also helpful for hair loss