I agree with Andrew you cannot specifically say "this will get you huge" as no matter what method of training you do your body will adapt to it and your progress will stagnate. By constantly fluctuating your workouts it will keep the body guessing and hence responding. A general rule of thumb though is heavy weights and low reps equals large muscles. This is simply because in order to constantly adapt to heavier poundages, the body must grow bigger and stronger. Lighter weights and high reps I have found have never done much for growth (at least after you have been training for awhile) but are necessary to work the long and short muscle fibres. I have never seen a huge guy emerge from working with light weights. In fact there is a guy I know who has been training for years, weighs about 220 at 5' 9'', he is a good size but he has been on juice for years and never changes. I have noticed that he never lifts heavy, so I asked him why. His excuse was he has injuries everywhere and cannot lift heavy any longer. He says he has been stuck at the same weight for years! Now when he achieved all his gains he used to lift heavy. Do the two go together, well try it yourself and you will know. I know I never grow much from high reps, but I sure explode from lifting heavy! I look at it this way, rep ranges from 1 - 4 are mostly for strength (powerlifters like this range) 5 - 8 combine heavy lifts with higher rep range for strength and mass (say 60 - 80% of your max) and 9 to 15 are for definition training and endurance. Now this is how my body responds but I think this would be a accurate rep range for most!