BigBob
AnaSCI VET / Donating Member
- Nov 10, 2012
- 2,904
- 0
- 36
Me too. Sometimes its dark but not always. And I have never had tren cough.....I guess we are all different, I'm curious what that difference is though.
Home | Forums | AnaPRO Shop | F.A.Q | Injecting | Advertising | Contest Winners | Newsletters | Contact Us | Videos |
Me too. Sometimes its dark but not always. And I have never had tren cough.....I guess we are all different, I'm curious what that difference is though.
With all the great gear out there how about just dont run any orals?
Whatever you're just mad because I wouldn't let u come live with me.Shut up mr negative. .lol. E this is a bad thread. Lol. :delete:
Shut up mr negative. .lol. E this is a bad thread. Lol. :delete:
Ummm you're on my coast now- watch yourself I may just come down there and go hunting for swamp ape... You're Yetti no more- you're " Swamp Ape"
So after quite a bit of research, I've learned there is no way for an injected oral to be subject to first pass liver metabolization.
This is a simply matter of plumbing-
Once something is ingested... It's broken down in the stomach, then moves into the small intestine where it's absorbed into the blood stream and then is shuttled via hepatic portal vein into the liver for metabolization.
This is the only way something would be subject to first pass metabolization- if you administer a drug via intramuscular injection then it's absorbed directly and by passes the liver.
So from a physiological point of view- no injectable orals are not hepatoxic, but none the less they still impose a great deal of stress on the renal system.
Good post...
Tis better to shoot your winny than drink it....
but doesn't anything smoked, drank or injected pass thru via the bloodstream?
No thats not how it works at all. This is totally backwards rofl
:sFun_TVtrouble::sAng_badmood::sSig_Kewlpics:
Trenbolone, masteron, and other AAS could hard on the renal system. Theyre not good for your liver. Usually the more resistant a drug is to metabolism the more 'toxic' it is. There could also be liver damage caused by direct agonism at steroid receptor sites in the liver Liver Injury Induced by High-Dose Methylprednisolone Therapy: A Case Report and Brief Review of the Literature
First pass is only relevant for drugs that are completely broken down by the liver, like testosterone. If you take an anadrol it is still going to pass through your liver thousands of times whether it is injected or taken orally. Your blood is constantly passing through your liver.
So I guess you're right if you inject anadrol you could technically say it avoids first pass metabolism. But it is not important because even anadrol Inj. will pass through your liver thousands of times before being excreted.
Injecting anadrol and eating it is the same thing. The difference is anadrol Inj. gets released from the depot slowly. It could also be easier on your stomach. Some people get stomach aches from high dose orals.
Also, non 17methylated steroids could be damaging to liver. The 17methyl modification is not the only thing that causes liver toxicity. Liver toxicity is complicated and not well understood.
I think people use way too much dboll and anavar. I was on 75 mg tren Ace a day and 500 sust a week and 50mg of anavar ruined me. Dboll, I never have to go higher than 20mg. 4 Thai pinks and bam. I guess I'd your competing or in some comp than maybe.
And I agree high liver values without any other symptoms are quite normal when on many meds and even after heavy workouts.
First pass is only relevant for drugs that are completely broken down by the liver, like testosterone. If you take an anadrol it is still going to pass through your liver thousands of times whether it is injected or taken orally. Your blood is constantly passing through your liver.
So I guess you're right if you inject anadrol you could technically say it avoids first pass metabolism. But it is not important because even anadrol Inj. will pass through your liver thousands of times before being excreted.
Injecting anadrol and eating it is the same thing. The difference is anadrol Inj. gets released from the depot slowly. It could also be easier on your stomach. Some people get stomach aches from high dose orals.
Also, non 17methylated steroids could be damaging to liver. The 17methyl modification is not the only thing that causes liver toxicity. Liver toxicity is complicated and not well understood.
As I said earlier this is only relevant to drugs which must be administered IM or subQ like testosterone. You are incorrect. Do more research about the renal and circulatory systems in general.
It is my understanding that butthole69 is correct. If a compound, whether AAS, alcohol, acetaminophen, or whatever, is a type that is broken down by the liver, then it is going to be broken down by your liver.
Whether you inject it, snort it, drink it, or shove it up your ass, your liver still has to deal with 100% of it. There's no way around that.
If it's in your blood, it's going to go through your liver.
Where do half lives comes from? From how quickly compounds are metabolized or "broken down" by the liver. Injectable versions of orals have the same half lives as the oral version because.....