Yes, Ralox will take time, typically 3 months. Puberty gyno is a whole other ballgame. Letro is quite a harsh compound, and too often when used by inexperienced users, it leads to greater complications. Letro has it's place in our world, but I personally would keep it away from gyno-related concerns.
It's funny you say that- from my experience and that of others I've dealt with- seems as though Letro (while being quite harsh) is the best method. Nandi did quite a bit of research on this and concluded as well that a total elimination of estrogen was essential to halt the development of permanent glandular fibrosis.
In reality, the etiology of gynecomastia is still unknown and a number of agents including estrogens, progestins, GH, IGF-1, and prolactin may be involved. However, most research and anecdotal evidence supports the belief that a decreased (T+DHT)/E ratio is central to the development of gyno, and that blocking the effects of estrogen, or increasing T + DHT levels, is central to ameliorating the problem.
That being said, an antagonist of the alpha and beta ER's will not suffice, while to some degree it may halt the progression of tissue proliferation- it still lacks the ability to alter the pathology which induced the gyno to begin with. Also taking a long approach to the problem also allows for the possibility for the tissue to gain some "permanence"
Bottom line is that the pathology of gyno the manipulation of hormones that play into the pathways is the most important aspect of treatment. This is why my protocol has a high dose of DHT derivatives (in order to suppress the transcription of E2 in ER-a and ER-b) and a high and aggressive dosing of aromatase enzyme inhibitor.