When using DMSO, it's all about purity. No one should ever use the stuff that comes from an animal supply store, nor should we be using the stuff that comes from eBay. It needs to be pharmaceutical grade only. And yes, there is pharmaceutical DMSO. DMSO is available as a prescribed treatment for interstitial cystitis. Basically a really bad bladder infection. The only DMSO I would ever use comes from Jacob Lab. It is pharmaceutical grade DMSO, from a reputable company. Their DMSO should not cause any burns, irritation, or ill effects. A slight sulphury garlic odor will occur with any DMSO, though, although theirs is much less pronounced.