Ok I am interested to determine how long one can stay on a cycle for, safely mind you, so i would like to hear everyones experiences. I was postulating what Big A wrote about the only reason to go off is due to health reasons or you stop growing (your receptors get saturated, although I have read an interesting article saying this is a myth!). Anyways looking forward to hearing everyones experiences! My longest cycle was 6 months, and 45lbs of quite lean muscle (my ulcerative colitus kicked in about 3 months post cycle and I lost about 30 lbs, can't maintain muscle when you cannot eat!).