I disagree. 0.1mg is so low that it would make the trip before getting broken down.
??? sorry, what do you mean?
Plus real pills if you have them are timed release. So if you cut it, you will be just wasting your time.
Interesting, I don't know why they would bother adding ethyl cellulose polymers to the drug to extend it's release of the active chemical by several
hours when the drug itself has a half-life of around 4
days? Or even though ethl-cellulose polymers are the most effective form of time-release technology and has been the standard since 2002 - I do not understand why any form of time-release technology would benefit this drug; do you think that it causes the pill itself to sit around for days? Cutting it or even chewing it will have no effect unless you are passing the pill in your stool undisolved!
where did you get your research stating that 0.1mg is effective?
One of many resources that shows that .1mg letrozole causes 74% estradiol and 79% estone decrease after one day while: .5mg caused 82% and 84.1%, and 2.5mg caused 81% and 68%.
After 1 week - .1mg through 5mg all achieved greater than 95% suppression.
erc.endocrinology-journals.org/cgi/reprint/6/2/245.pdf
Plus it would not lower your sex drive, but probably increase it. Femara is also used to help woman get prego until it was recall by the FDA due to the facts it causes birth defects
So many things wrong with this.
First - It was never approved by the FDA for use in infertility, it was and is a off-label use.
Second - how could anyone come to the conclusion that because a drug is used to increase ovulation that it would increase sex drive, plus given the fact that .1mg a day causes a 95% suppression of estrogen which is needed to maintain sex drive...... here's a quote from someone else as I do not have the time or desire to dig up studies as I do not get paid for this:
An effective dose of Letrozole (Femara) is .25-.5mg/day (I use .25mgs/day), but be forewarned, if you go over that amount, it can kill your sex drive. ANTHONY ROBERTS
Some other resources you might want to look into when you have the time or desire:
cancer.med.upenn.edu/resources/article.cfm?c=3&s=8&ss=23&id=1519&month=08&year=2001
J Clin Endocrinol Metab. 1995 Sep;80(9):2658-60
cancer.adisonline.com/pt/re/onc/abstract.00024669-200201050-00007.htm;jsessionid=FlPTCrjmhgFCvL14LWsZzxcdPJ1G8J1wHR3yZ6BJ9FhhBL6hwTS2!380829556!-949856145!8091!-1
erc.endocrinology-journals.org/cgi/reprint/6/2/245.pdf
ANY profile posted on the internet on letrozole (femara)
And an interesting chart showing the testosterone boost from letrozole (femara)
· 0.02 mg of Letrozole increased testosterone by 45% after 2 days
· 0.1 mg of Letrozole increased testosterone by 49% after 2 days
· 0.5 mg of Letrozole increased testosterone by 48% after 2 days
· 1 mg of Letrozole increased testosterone by 41% after 2 days
· 2.5 mg of Letrozole increased testosterone by 74% after 3 days
· 10 mg of Letrozole increased testosterone by 97% after 2 days
· 30 mg of Letrozole increased testosterone by 113% after 3 days
Sorry if this comes off too strong, but misinformation, especially dealing with a drug that can adversly affect someones health is not something to mess around with. Estrogen is needed in your body to maintain vascular structure and elasticity, cholesterol levels, bone health, joint health, heart health, and yes SEX DRIVE. Letrozole really shouldn't even be used with the cycle outlined unless someone is extremely sensitive to gyno, it's all they have, or they are wanting to remove all most all of the estrogen in their body for a competition, photo shoot, etc.